Disturbance in career often is very much disturbing, all of sudden there may be change of job or loss of job for known or unknown reasons. Astrologically disturbances in career happens due to ill placement of 10th lord from lagna, bad planet placed in 10th bhava and trik lord influence on 10th house. Trigger is caused by running dasha antardasha and transist Saturn sun or Rahu/Ketu.
If 10th lord placed in own and sthira rashi normally there is gradual growth in career in respective antardasha , if affected by Rahu it cause sudden loss or change of career.
If 10th house shared by more than one planet and if they are strong enough there may be multiple source of income and sometime there may be total change in profession